Correct Answer - A
Answer is A (Most common in Left Atrium)
Cardiac Myxomas are usually located in the atria, most common in
the left.
Cardiac myxomas
Are the most common type of primary cardiac tumorsQ
Occur at all ages and show no sex preference (mixes equally with
both sexes)
Q Most cardiac myxomas are sporadic, while some may be
familial

Sporadic myxomas :
Are solitary Q
Located in Atria, most commonly in the left Q
Unlikely to have post-op recurrence Occur in younger individuals Q

Familial myxomas :
Are multiple °
More likely to have post op recurrence e
Myxomas are benign tumors and therefore distant metastasis are
not seen.

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Correct Answer - A
Answer- A. Duct ectasia
TREATMENT

Hadfield’s operation- excision of all major ducts
Antibiotics- amoxiclav and metronidazole

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Correct Answer - D
Ans. is 'd' i.e., Tumor plop sound
Low pitch heart sounds are :
S3
S4
Tumor plop sound

Mid systolic clicks are
Heard in mitral valve prolapse during systole and are high pitch
sounds.

The pericardial knock (PK) is
Also high-pitched and occurs slightly later than the opening snap, corresponding in timing to the abrupt cessation of ventricular
expansion after tricuspid valve opening and to an exaggerated y
descent seen in the jugular venous waveform in patients with
constrictive pericarditis.

A tumor plop is
A lower-pitched sound that can be heard in patients with atrial
myxoma.
It may be appreciated only in certain positions and arises from the diastolic prolapse of the tumor across the mitral valve

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Correct Answer - C
Ans. is 'c' i.e., Desmoplasia

In some tumor, parenchymal cell stimulate the formation of an abundant collagen stroma refferd to as desmoplaisa
Eg.schirruos tumor of breast

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Correct Answer - A
Answer- A. Cisplatin
Cisplatin is used in the management of Hodgkins lymphoma, non Hodgkins lymphoma and small cell carcinoma of lung.

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Correct Answer - C
Ans. C: Anti-mitochondrial

Primary biliary cirrhosis is strongly associated with the presence of
anti-mitochondrial antibodies (AMA), which are diagnostic
PBC:
* Associated with CREST syndrome, sicca syndrome, auto-immune
thyroiditis, type I DM and IgA deficiency
* IgG AMA is detected in more than 90% of patients with PBC
* 90% of women are between 35 - 60 years
* Earliest symptom is pruritis
* Eventually hepatocellular failure and portal hypertension develops
* Lab findings:
- Increased serum alkaline phosphatase
- Increased serum 5-nucleotidase activity
- Increased gamma-glutamyl transpeptidase
- Serum bilirubin is usually normal
- Aminotransferase levels minimally increased
- Treatment: Ursodiol


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Correct Answer - B
Ans: B. PML-RARA

All-trans retinoic acid (ATRA) is an active metabolite of vitamin A
under the family retinoid.

Retinoids, through their cognate nuclear receptors, exert potent
effects on cell growth, differentiation and apoptosis, and have significant promise for cancer therapy and chemoprevention.

Differentiation therapy with ATRA has marked a major advance and
become the first choice drug in the treatment of acute promyelocytic
leukemia (APL).

All-trans retinoic Acid is used in the treatment for Acute Promyelocytic Leukemia (PML)

@oncology_vid

Correct Answer - C
Ans. is 'c' i.e., Craniophyrangioma

Craniophyrangioma leads to central diabetes mellitus and resultant
loss of water leads to hypernatremia

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Correct Answer - C
Answer- C. Colorectal cancer
Colon and rectal tumors Streptococcus bovis (bacteremia

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Correct Answer - A
Ans. is 'a' i.e., Intron 1 inversion

Thalassemias are autosomal recessive disorder
The most common mutation causing 13 thalassemias is
intron/inversion


Also know:
Synthesis of alpha chain is controlled by 2 gene clusters on →
Chromosome 16
Synthesis of beta chain is controlled by 2 gene clusters on →
Chromosome 11
Thalassemia mutations in India

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